Month: November 2013

Good Doctors...Better People

Nephrology Board Review – Membranous Nephropathy

1.) How many histologic stages of Membranous Nephropathy are there? A. 2 B. 3 C. 4 D. 5   2.) The stages correlate with the clinical manifestations of MN. A. True B. False   3.) Which of the following are podocyte antigens? A. suPAR B. Neutral endopeptidase (NEP) C. Paxillin D. Phospholipase A1 Receptor (PLA2R)…
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Factors Associated with Worse Renal Survival in Membranous Nephropathy

At the moment we don’t have clinically available serologic markers of disease activity for membranous nephropathy (PLA2R is in the pipeline) so we have to rely on clinical factors to predict prognosis. Above is a chart that lists the factors associated with Progression and strength of the associated (PPV). Source: Comprehensive Clinical Nephrology, 4th Edition.

CKD and Dietary Recommendations

Typical Dietary Recommendations for Chronic Kidney Disease Patients Protein: 0.6-0.8 g/kg/day Sodium: <2 g/day (<6 g/day of salt) Potassium: 40-70 mEq/day Phosphate: 600-800 mg/day Calcium: 1400-1600 mg/day (not to exceed 2000 mg/day) Free water (in excess of urine output): 1-1.5 L/day Here is a great chart of dietary recommendations by the Cleveland Clinic’s Disease Management…
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