After much adieu, JNC8 has finally been released and here are some of the new reccommendations: In patients 60 years or over, start treatment in blood pressures >150 mm Hg systolic or >90 mm Hg diastolic and treat to under those thresholds. In patients 18 years with either chronic kidney disease (CKD) or diabetes. In…
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1.) How many histologic stages of Membranous Nephropathy are there? A. 2 B. 3 C. 4 D. 5 Discussion: Four stages. Great LM and EM can be found here (AKJD Atlas). Stage I: Subepithelial deposits with little change to GBM, but extensive foot process effacement Stage II: Basement membrane “spikes” form between immune-complex Stage…
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Here is a great review of Loin Pain Hematuria Syndrome from one of our fellows, Saqib Syed. Bullet Points Mostly women Diagnosis of Exclusion (rule out infection, glomerular disease, stones, tumor, cyst, cystitis, AV malformation, hemangioma, ureteral pathology, coagulopathy, and factious disease. One of the few disease where nephrectomy and autotransplantation are may be indicated…
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Thrombotic microangiopathies (or TMA for the cool kids or the occasional phonetically-challenged fellows like myself) have always been a little tricky so I decided to do a quick review today to help clear things up a bit. First I’ll start with some questions and try to jump into the meat of things. Question 1 A…
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The Mountain View based 23AndMe, a personal genome service (PGS) that offers genome sequencing was ordered to stop marketing its service. The FDA report stated that 23AndMe did not demonstrate that they had “analytically or clinically validated the PGS for its intended uses” and the “FDA is concerned about the public health consequences of…
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