This is a quick powerpoint/google slide of a MGRS presentation I did on last week for grand rounds. It probably isn’t super effective without the audio so I may convert it to full out post once I get some time. But there are about 10 solid (at least to me) MGRS/MGUS questions to help quickly…
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A 58 y/o F with history of HTN presents to an outside hospital for pancreatitis and LE edema. While there patient is found to have Hep C (genotype 3). After protracted course due to no improvement in pancreatitis she is transferred to our hospital. While here, a UA is done which shows 3+ proteins and…
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As I’ve been studying I’ve been trying to make up questions of information that I found to be important or interesting (at least to me). These questions and those to follow are a random grouping of multiple choice, true/false, or guess what I’m thinking. 1.) Collapsing FSGS is associated with what disease/drugs? 1.) HIV 2.)…
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Collapsing FSGS is associated with what disease/drugs? 1.) HIV 2.) Parvovirus B19 infection 3.) Interferon therapy 4.) Pamidronate toxicity
As I’ve been studying I’ve been trying to make up questions of information that I found to be important or interesting (at least to me). These questions and those to follow are a random grouping of multiple choice, true/false, or guess what I’m thinking. 1.) Collapsing FSGS is associated with what disease/drugs? 2.) Which monosaccharide…
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Primary Causes FSGS Membranous Membranoproliferative Ig A Minimal Change Disease Secondary Causes Diabetic Nephropathy Lupus Nephropathy Amyloidosis/Light Chain Deposition Disease HIV(membranous, membranoproliferative, FSGS)
Commonly in the work up of nephrotic syndrome we think serum complements are ordered because they help us narrow down our differential diagnosis. Here is a quick reminder of which conditions cause what. As a quick reminder remember that classical activation involves the binding of C1q to the Fc region of IgG and IgM…
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1.) How many histologic stages of Membranous Nephropathy are there? A. 2 B. 3 C. 4 D. 5 Discussion: Four stages. Great LM and EM can be found here (AKJD Atlas). Stage I: Subepithelial deposits with little change to GBM, but extensive foot process effacement Stage II: Basement membrane “spikes” form between immune-complex Stage…
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At the moment we don’t have clinically available serologic markers of disease activity for membranous nephropathy (PLA2R is in the pipeline) so we have to rely on clinical factors to predict prognosis. Above is a chart that lists the factors associated with Progression and strength of the associated (PPV). Source: Comprehensive Clinical Nephrology, 4th Edition.
“What should I eat?” And “Should I avoid protein since I’m losing it in my urine?” These are questions that I often hear my patients with nephrotic syndrome ask. So today I decided to do a quick review to answer those questions in the clinic and on the wards. Sodium Sodium restriction has been shown…
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